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2012

the NHLBI ARDS Clinical Trials Network. 2012. Initial Trophic vs Full Enteral Feeding in Patients With Acute Lung Injury: The EDEN Randomized Trial. JAMA.

2011

Randolph, A, Vaughn F, Sullivan R, Rubinson L, Thompson BT, Yoon G, Smoot E, Rice T, Loftis L, Helfaer M et al.. 2011. Critically Ill Children During the 2009-2010 Influenza Pandemic in the United States. Pediatrics. 128(6)

Liu, KD, Thompson BT, Ancukiewicz M, Steingrub JS, Douglas IS, Matthay MA, Wright P, Peterson MW, Rock P, Hyzy RC et al.. 2011. Acute kidney injury in patients with acute lung injury: Impact of fluid accumulation on classification of acute kidney injury and associated outcomes. Crit Care Med.

Thompson, BT, Bernard GR. 2011. ARDS Network (NHLBI) Studies: Successes and Challenges in ARDS Clinical Research. Crit Care Clin. 27(3):459-468.

Clermont, G, Kong L, Weissfeld LA, Lave JR, Rubenfeld GD, Roberts MS, Connors Jr. AF, Bernard GR, Thompson BT, Wheeler AP et al.. 2011. The Effect of Pulmonary Artery Catheter Use on Costs and Long-Term Outcomes of Acute Lung Injury. PLoS ONE. 6(7):e22512.

Grams, ME, Estrella MM, Coresh J, Brower RG, Liu KD, the NHLBI. 2011. Fluid balance, diuretic use, and mortality in acute kidney injury. Clin J Am Soc Nephrol. 6(5):966-73.

Matthay, MA, Brower RG, Carson S, Douglas IS, Eisner M, Hite D, Holets S, Kallet RH, Liu KD, Macintyre N et al.. 2011. Randomized, Placebo-Controlled Clinical Trial of an Aerosolized Beta-2 Agonist for Treatment of Acute Lung Injury. Am J Respir Crit Care Med.

Britos, MF, Smoot E, Liu KD, Thompson BT, Checkley W, Brower RG. 2011. The value of positive end-expiratory pressure and FiO2 criteria in the definition of the acute respiratory distress syndrome. Crit Care Med.

Rice, TW, Ware LB, Haponik EF, Chiles C, Wheeler AP, Bernard GR, Steingrub JS, Hite RD, Matthay MA, Wright P et al.. 2011. Vascular pedicle width in acute lung injury: correlation with intravascular pressures and ability to discriminate fluid status. Crit Care. 15(2):R86.

Wang, W, Scharfstein D, Wang C, Daniels M, Needham D, Brower R, the NHLBI Acute Respiratory Distress Syndrome Clinical Trials Network. 2011. Estimating the causal effect of low tidal volume ventilation on survival in patients with acute lung injury. Journal of the Royal Statisitcal Society. 60(4):475-496.

Glavan, BJ, Holden TD, Goss CH, Black RA, Neff MJ, Nathens AB, Martin TR, Wurfel MM, ARDSnet Investigators. 2011. Genetic Variation in the FAS Gene and Associations with Acute Lung Injury. Am J Respir Crit Care Med. 183(3):356-63.

Parsons, EC, Hough CL, Seymour CW, Cooke CR, Rubenfeld GD, Watkins TR, the NHLBI ARDS Network. 2011. Red blood cell transfusion and outcomes in patients with acute lung injury, sepsis and shock. Crit Care. 15(5):R221.

2010

Bull, TM, Clark B, McFann K, Moss M, NIH NHLBI ARDS Network. 2010. Pulmonary vascular dysfunction is associated with poor outcomes in patients with acute lung injury. Am J Respir Crit Care Med. 182(9):1123-8.

Johnson, ER, Matthay MA. 2010. Acute lung injury: epidemiology, pathogenesis, and treatment. J Aerosol Med Pulm Drug Deliv. 23(4):243-52.

Checkley, W, Brower RG, Muñoz A, NIH Acute Respiratory Distress Syndrome Network Investigators. 2010. Inference for mutually exclusive competing events through a mixture of generalized gamma distributions. Epidemiology. 21(4):557-65.

Ware, LB, Koyama T, Billheimer DD, Wu W, Bernard GR, Thompson BT, Brower RG, Standiford TJ, Martin TR, Matthay MA et al.. 2010. Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury. Chest. 137(2):288-96.

Stapleton, RD, Dixon AE, Parsons PE, Ware LB, Suratt BT, the NHLBI Acute Respiratory Distress Syndrome Network. 2010. The Association Between BMI and Plasma Cytokine Levels in Patients with Acute Lung Injury. Chest. 138:568-577.

Calfee, CS, Gallagher D, Abbott J, Aird WC, Thompson BT, Matthay MA, the NHLBI ARDS Network. 2010. Plasma Angiopoietin-2 in Patients with Acute Lung Injury: Pathogenetic and Prognostic Significance. ATS.

2009

Grissom, C, Morris A, Lanken P, Ancukiewicz M, Orme J, Schoenfeld D, Thompson T. 2009. Association of Physical Examination with Pulmonary Artery Catheter Parameters in Acute Lung Injury R3. Critical Care Medicine. 37(10):2720-2726.

Kallet, RH. 2009. What is the legacy of the National Institutes of Health Acute Respiratory Distress Syndrome Network? Respir Care. 54(7):912-24.

Cooke, CR, Shah CV, Gallop R, Bellamy S, Ancukiewicz M, Eisner MD, Lanken PN, Localio AR, Christie JD, the NHLBI ARDS Network. 2009. A Simple Clinical Predictive Index for Objective Estimates of Mortality in Acute Lung Injury. Critical Care Medicine. 37(6):1913-20.

Stewart, RM, Park PK, Hunt JP, McIntyre RCJ, McCarthy J, Zarzabal LA, Michalek JE, the NIH NHLBI ARDS Clinical Trials Network. 2009. Less Is More: Improved Outcomes In Surgical Patients with Conservative Fluid Administration and Central Venous Catheter Monitoring. Journal of the American College of Surgeons. 208(5):725-35.

Erickson, SE, Shlipak MG, Martin GS, Wheeler AP, Ancukiewicz M, Matthay MA, Eisner MD. 2009. Racial and ethnic disparities in mortality from Acute Lung Injury. Critical Care Medicine. 37(1):1-6.

Hough, CL, Steinberg KP, Thompson TB, Rubenfeld GD, Hudson LD. 2009. Intensive care unit-acquired neuromyopathy and corticosteroids in survivors of persistent ARDS. Intensive Care Medicine. 35(1):63-8.

Erickson, SE, Martin GS, David JL, Matthay MA, Eisner MD, the NIH NHLBI ARDS Network. 2009. Recent trends in acute lung injury mortality: 1996-2005. Crit Care Med. 37(5):1574-9.

Rosenberg, AL, Dechert RE, Park PK, Bartlett RH, the NIH NHLBI ARDS Network. 2009. Review of a large clinical series: association of cumulative fluid balance on outcome in acute lung injury: a retrospective review of the ARDSnet tidal volume study cohort.. Journal of Intensive Care Medicine. 24(1):35-46.

2008

Glassberg, AE, Luce JM, Matthay MA, the NHLBI Clinical Trials Network. 2008. Reasons for Nonenrollment in a Clinical Trial of Acute Lung Injury. Chest. 134(4):719-23.

Matthay, MA. 2008. Treatment of acute lung injury: clinical and experimental studies. Proc Am Thorac Soc. 15(5):297-9.

Arroliga, AC, Thompson BT, Ancukiewicz M, Gonzales JP, Guntupalli KK, Park PK, Wiedemann HP, Anzueto A, the NHLBI ARDS Network. 2008. Use of sedatives, opioids, and neuromuscular blocking agents in patients with acute lung injury and acute respiratory distress syndrome. Critical Care Medicine. 36(4):1083-8.

Checkley, W, Brower R, Korpak A, Thompson BT. 2008. Effects of a clinical trial on mechanical ventilation practices in patients with acute lung injury. Am J Respir Crit Care Med. 177:1215-1222.

Calfee, CS, Ware LB, Eisner MD, Parsons PE, Thompson BT, Wickersham N, Matthay MA, the NHLBI ARDS Network. 2008. Plasma Receptor for Advanced Glycation End-Products And Clinical Outcomes in Acute Lung Injury. Thorax. 63(12):1083-9.

Calfee CS, Eisner MD, Parsons PE, Thompson BT, Conner ERJ, Matthay MA, Ware LB, the NHLBI ARDS Network. 2008. Soluble intercellular adhesion molecule-1 and clinical outcomes in patients with acute lung injury. Intensive Care Med. epub.

2007

Calfee, CS, Eisner MD, Ware LB, Thompson BT, Parsons PE, Wheeler AP, Korpak A, Matthay MA, Network ARDS, National Heart Lung et al.. 2007. Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders. Crit Care Med. 35(10):2243-50.

Calfee, CS, Budev MM, Matthay MA, Church G, Brady S, Uchida T, Ishizaka A, Lara A, Ranes JL, deCamp MM et al.. 2007. Plasma receptor for advanced glycation end-products predicts duration of ICU stay and mechanical ventilation in patients after lung transplantation. Heart Lung Transplant. 26(7):675-80.

Ware, LB, Matthay MA, Parsons PE, Thompson BT, Januzzi JL, Eisner MD. 2007. Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome.. Crit Care Med. . 35(8):1821-8.

Kallet, RH, Branson RD. 2007. Respiratory controversies in the critical care setting. Do the NIH ARDS Clinical Trials Network PEEP/FIO2 tables provide the best evidence-based guide to balancing PEEP and FIO2 settings in adults? Respir Care. 52(4):461-75.

Rice, TW, Wheeler AP, Bernard GR, Hayden DL, Schoenfeld DA, Ware LB, the NIH NHLBI ARDS Network. 2007. Comparison of the Sp02/FI02 Ration and the PaO 2/FI02 in Patients with Acute Lung Injury or ARDS. Chest. 132(2):410-417.

McClintock, DE, Ware LB, Eisner MD, Wickersham N, Thompson BT, Matthay MA, the NHLBI ARDS Network. 2007. Higher urine nitric oxide is associated with improved outcomes in patients with acute lung injury. American Journal of Respiratory and Critical Care Medicine. 175(3):256-62.

Calfee, CS, Matthay MA. 2007. Nonventilatory treatments for acute lung injury and ARDS. Chest. 131(3):913-20.

Liu, KD, Glidden DV, Eisner MD, Parsons PE, Ware LB, Wheeler A, Korpak A, Thompson BT, Chertow GM, Matthay MA et al.. 2007. Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury. Critical Care Medicine. 35(12):2755-2761.

Thompson, BT, Schoenfeld D. 2007. Usual care as the control group in clinical trials of nonpharmacologic interventions. Proc Am Thorac Soc. 4:577-582.

2006

Steinberg, KP, Hudson LD, Goodman RB, Hough CL, Lanken PN, Hyzy R, Thompson BT, Ancukiewicz M, ARDSNet NIHNHLBI/. 2006. Efficacy and Safety of Corticosteroids for Persistent Acute Respiratory Distress Syndrome. New Engl J Med. 354(16):1671-1684.

Wiedemann, HP, Wheeler AP, Bernard GR, Thompson BT, Hayden D, deBoisblanc BP, Connors Jr. AF, Hite RD, Harabin AL, ARDSNet NIHNHLBI/. 2006. Comparison of Two Fluid-Management Strategies in Acute Lung Injury. New Engl J Med. 354(24):2564-2575.

Wheeler, AP, Bernard GR, Thompson BT, Schoenfeld DA, Wiedemann HP, deBoisblanc BP, Connors Jr. AF, Hite RD, Harabin AL, ARDSNet NIHNHLBI/. 2006. Pulmonary-Artery Versus Central Venous Catheter to Guide Treatment of Acute Lung Injury. New Engl J Med. 354(21):2213-2224.

Rice, TW, Wheeler AP, Bernard GR, Ware LB, the NIHNHLBIARDSN. 2006. Comparison of SpO2/FiO2 ratio to PaO2/FiO2 ratio in the diagnosis of ALI and ARDS. ATS. Abstract

Grissom, CK, Morris AH, Lanken PN, Orme JF, Schoenfeld DA, Thompson BT, ARDSNet NIHNHLBI/. 2006. Correlation of clinical exam findings and cardiac index in patients with ARDS. CHEST.

deBoisblanc, BP, Brierre SP, Hayden D, ARDSNet NIHNHLBI/. 2006. Discordance of central venous pressure (CVP) vs. pulmonary artery occlusion pressure (PAOP) pressure range assignment in patient. ATS. Abstract

McClintock, D, Starcher B, Eisner MD, Thompson BT, Hayden D, Church GD, Matthay MA. 2006. Higher Urine Desmosine Levels are Associated with Mortality in Patients with Acute Lung Injury. Am J Physiol Lung Cell Mol Physiol.

Glassberg, AE, Luce JM, Matthay MA, ARDSNet NIHNHLBI/. 2006. The impact of lacking a surrogate on enrollment in NHLBI clinical trials of acute lung injury. ATS. Abstract

Hite, RD, Seeds MC, Grier BL, Morris PE, Goodman RB, Schoenfeld DA. 2006. Impact of steroids on surfactant in persistent ARDS (ARDSNet LaSRS Trial). ATS. Abstract

Truwit, JD, Korpak A, Schoenfeld DA, Matthay MA, Peterson M, Writght P, Rock P, Anzueto A, Hyzy R, Steingrub J et al.. 2006. Incidence and impact on mortality of acute renal dysfunction after the onset of acute lung injury. ATS. Abstract

Trimarchi, T, Petty JM, Young MP, Allen GB, Parsons PE, Suratt BT, ARDSNet NIHNHLBI/. 2006. Plasma G-CSF levels are associated with mortality in ALI/ARDS. ATS. Abstract

Christie, JD, Localio AR, Bellamy S, Gallop R, Ancukiewicz M, Schoenfeld DA, Eisner MD, Lanken PN, ARDSNet NIHNHLBI/. 2006. A simple clinical predictive index for objective estimates of mortality in acute lung injury (ALI). CHEST.

2005

Hayden, D, Pauler DK, Schoenfeld DA. 2005. An Estimator for Treatment Comparisons Among Survivors in Randomized Trials. Biometrics. 61(1):305-310.

Rizvi, K, deBoisblanc BP, Truwit JD, Dhillon G, Arroglia AC, Fuchs BD, Guntupalli KK, Hite RD, Hayden D, ARDSNet NIHNHLBI/. 2005. Effect of Airway Pressure Display on Interobserver Agreement in the Assessment of Vascular Pressures in Patients with Acute Lung. Crit Care Med. 33(1):98-103,discussion243-2.

Lee, CM, Kallet RH, Ranieri VM, Rubenfeld GD, Luce JM, Hudson LD. 2005. Intrinsic Positive End-Expiratory Pressure in Acute Respiratory Distress Syndrome (ARDS) Network Subjects. Crit Care Med. (33):3.

Pellett, AA, Welsch DA, deBoisblanc BP, Lipscomb G, Johnson RW, Lord KC, Levitzky MG. 2005. Low Positive End-Expiratory Pressure Does Not Exacerbate Nebulized-Acid Lung Injury in Dogs. J Crit Care. 20(1):97-105.

Friedman, D, deBoisblanc BP, Arroglia AC, Fuchs BD, Guntupalli KK, Hite RD, Truwit JD. 2005. Accuracy of airway pressure display for identification of end-expiration during the measurement of CVP and PAOP in mechanically-. ATS. Abstract

Morris, AH, Sorenson D, Warner HR, Day JA, Korpak A, Orme JF, Clemmer T, Thompson BT, Schoenfeld DA. 2005. Bedside computerized study protocols for an ARDS Network clinical trial. ATS. Abstract

Parsons, PE, Matthay MA, Ware LB, Eisner MD. 2005. Elevated Plasma Levels of Soluble TNF Receptors are Associated with Morbidity and Mortality in Patients with Acute Lung Injury. Am J Physiol Lung Cell Mol Physiol. 288:L426-431.

Parsons, PE, Eisner MD, Thompson BT, Matthay MA, Ancukiewicz M, Bernard GR, Wheeler AP. 2005. Lower Tidal Volume Ventialtion and Plasma Cytokine Markers of Inflammation in Patients with Acute Lung Injury. Crit Care Med. 33:1-6,discussion230-232.

Hager, DN, Krishman JA, Hayden D, Brower RG, ARDSNet NIHNHLBI/. 2005. Tidal Volume Reduction in Patients with acute Lung Injury When Plateau Pressures Are Not High. Am J Resp Crit Care Med. 172:1241-1245.

2004

Ware, LB, Eisner MD, Thompson BT, Parsons PE, Matthay MA, ARDSNet NIHNHLBI/. 2004. Significance of von Willebrand Factor in Septic and Non-Septic Patients with Acute Lung Injury. Am J Resp Crit Care Med. :ePub.

Brower, RG, Lanken PN, MacIntyre NR, Matthay MA, Morris AH, Ancukiewicz M, Schoenfeld DA, Thompson BT, ARDSNet NIHNHLBI/. 2004. Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome. New Engl J Med. 351(4):327-336.

Rubenfeld, GD, Cooper C, Carter G, Thompson BT, Hudson LD. 2004. Barriers to Providing Lung Protective Ventilation to Patients with Acute Lung Injury. Crit Care Med. 32(6):1289-1293.

Lanken, PN, Ancukiewicz M, Christie JD, ARDSNet NIHNHLBI/. 2004. Baseline risk factors for mortality in 902 subjects with acute lung injury (ALI)/Acute Respiratory Distress Syndrome (ARDS). ATS. Abstract

Brower, RG, Thompson BT, Ancukiewicz M, ARDSNet NIHNHLBI/. 2004. Clinical trial of mechanical ventilation with traditional versus lower tidal volumes in acute lung injury and acute respiratory . ATS. Abstract

deBoisblanc, BP, Vuchs B, Truwit JD, Wiedemann HP, Hayden D, ARDSNet NIHNHLBI/. 2004. Effect of fluid balance on central venous pressure (CVP) and pulmonary artery occlusion pressure (PAOP) in patients with acute l. ATS. Abstract

Ringwood, NJ, Hayden D, Schoenfeld DA, ARDSNet NIHNHLBI/. 2004. Effects of gender and ethnicity on mortality in ALI and ARDS. ATS. Abstract

Ware, LB, Eisner MD, Wickersham N, Olman MA, Thompson BT, Parsons PE, Matthay MA, ARDSNet NIHNHLBI/. 2004. Plasminogen activator inhibitor-1 (PAI-1), a marker of impaired fibrinolysis, is associated with higher mortality in patients wi. ATS. Abstract

Silverman, HJ, Luce JM, Lanken PN, Morris AH, Oldmixon CF, Thompson BT, Bernard GR, ARDSNet NIHNHLBI/. 2004. Recommendations for informed consent forms (ICFs) for critical care trials. ATS. Abstract

Thompson, BT, Hayden D, Schoenfeld DA, ARDSNet NIHNHLBI/. 2004. Safety is not improved with the inclusion of a usual care arm in ICU trials. ATS. Abstract

2003

Brower, RG, Rubenfeld GD, Thompson BT. 2003. Meta-analysis of tidal volumes in ARDS (comment). Am J Resp Crit Care Med. (168):2.

deBoisblanc, BP, Girod-Espinoza A, Welsh D, Taylor D. 2003. Hemodynamic monitoring in ALI/ARDS. Respir Care Clin. 9(457-479)

Thompson, BT. 2003. Acute Respiratory Distress Syndrome. Merck Manual of Medical Information.

Thompson, BT. 2003. Corticosteroids and Acute Lung Injury. Crit Care Med. 31:S253-257.

Rizvi, K, deBoisblanc BP, Dhillon G, Arroglia AC, Fuchs BD, Guntupalli KK, Hite RD, Truwit JD, ARDSNet NIHNHLBI/. 2003. Effect of airway pressure display on inter-observer variability in assessment of vascular pressure in ARDSNet Fluids and Cathete. ATS. Abstract

Brower, RG, Morris AH, MacIntyre NR, Matthay MA, Hayden D, Thompson BT, Clemmer T, Lanken PN, Schoenfeld DA, ARDSNet NIHNHLBI/. 2003. Effects of Recruitment Maneuvers in Patients with Acute Lung Injury and Acute Respiratory Distress Syndrome Ventilated with High. Crit Care Med. 31(11):2592-2597.

Brower, RG, Krishman JA, Thompson BT, Wheeler AP, Wiedemann HP, Schoenfeld DA, Bernard GR. 2003. Effects of tidal volume reduction (Vt-R) in Acute Lung Injury (ALI) patients with inspiratory plateau pressures (Pplat) < 32 cm . ATS 2003. Abstract

deBoisblanc, BP, Pellett AA, Johnson RW, Champagne MS, McClarity E, Dhillon G, Levitzsky MG. 2003. Estimation of pulmonary artery occlusion pressure by an artificial neural network. Crit Care Med. 31(1):261-266.

Morris, AH, Silverman HJ, Stanholtz C, Brower RG, Thompson BT, Bernard GR, ARDSNet NIHNHLBI/. 2003. Experimental design and ethical issues for non-blinded ICU randomized controlled clinical trials. ATS. Abstract

Goss, CH, Brower RG, Hudson LD, Rubenfeld GD, ARDSNet NIHNHLBI/. 2003. Incidence of Acute Lung Injury in the United States. Crit Care Med. 31(6):1607-1611.

Verberes, L, Karir V, Day D, Polissar N, Spencer T, Cooper C, Neff MJ, Rubenfeld GD. 2003. Lung protective ventilation (LPV) for acute lung injury (ALI) does not increase sedation use. Crit Care Med. Abstract

Eisner, MD, Parsons PE, Matthay MA, Ware LB, Greene K, ARDSNet NIHNHLBI/. 2003. Plasma Surfactant Protein Levels and Clinical Outcomes in Patients with Acute Lung Injury. Thorax. 58:983-988.

Ware, LB, Ancukiewicz M, Parsons PE, Matthay MA, ARDSNet NIHNHLBI/. 2003. Prognostic value of of plasma protein C levels in patients with acute lung injury. ATS. Abstract

Eisner, MD, Parsons PE, Matthay MA, Ware LB, Greene K, ARDSNet NIHNHLBI/. 2003. Prognostic value of plasma surfactant protein D level for clinical outcomes in patients with acute lung injury. ATS. Abstract

Satsangi, S, Weir CF, Tesseyman SP, Morris AH. 2003. Proposed constructs that predict use of computerized protocols by ICU clinicians. ATS. Abstract

Brower, RG, Matthay MA, Bernard GR. 2003. Questions about ARDS Network trial of low tidal volume. Am J Resp Crit Care Med. 167:1717-1718.

Thompson, BT, Brower RG, Wheeler AP, Wiedemann HP, Schoenfeld DA, Bernard GR, ARDSNet NIHNHLBI/. 2003. Standard care prior to entry in ARDS Network studies encompassed wide variation in tidal volumes (Vt) and plateau pressures (Ppl. ATS. Abstract

2002

Suchyta, M, Aronsky DA, Dean NC, Orme JF, Jepson A, Morris AH. 2002. Community-acquired pneumonia and the incidence of ARDS. ATS.

Thompson, BT, Connors Jr. AF, Harabin AL, Hite RD, Wheeler AP, Wiedemann HP, ARDSNet NIHNHLBI/. 2002. Feasibility and safety of the ARDS Network's fluid and catheter treatment trial (FACTT). ATS.

Morris, AH, Sorenson D, Orme JF, Clemmer T, Weaver L, Grissom CK, Warner HR. 2002. A frame-based tool set for computerized protocols. ATS.

ARDSNet, NIHNHLBI/. 2002. Randomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome. Crit Care Med. 30(1):1-6.

Eisner, MD, Thompson BT, Schoenfeld DA, Anzueto A, Matthay MA. 2002. Airway Pressures and Early Barotrauma in Patients with Acute Lung Injury and the Acute Respiratory Distress Syndrome. Am J Resp Crit Care Med. 165(7):978-982.

Wiedemann, HP, Connors Jr. AF, Harabin AL, Hite RD, Thompson BT, Wheeler AP, ARDSNet NIHNHLBI/. 2002. Baseline hemodynamic characteristics of patients enrolled in the ARDS Network's fluid and catheter treatment trial (FACTT). ATS 2002. Abstract

Morris, AH. 2002. Decision Support and Safety of Clinical Environments. Quality and Safety in Health Care. 11:69-75.

Kallet, RH, Luce JM. 2002. Detection of Patient-Ventilator Asynchrony During Low Tidal Volume Ventilation, Using Ventilator Waveform Graphics. Respir Care. 47(2):183-185.

Brower, RG. 2002. Mechanical ventilation in acute lung injury and ARDS. Tidal Volume Reduction. Crit Care Med. 18(1):1-13.

Brower, RG, Matthay MA, Schoenfeld DA. 2002. Meta-analysis of acute lung injury and acute respiratory distress syndrome trials. Am J Resp Crit Care Med. 166(11):1515-1517.

Pellett, AA, Lord K, Champagne MS, deBoisblanc BP, Johnson RW, Levitzsky MG. 2002. Pulmonary Capillary Pressure During Acute Lung Injury in Dogs. Crit Care Med. 30:403-409.

Ely, EW, Wheeler AW, Thompson BT, Steinberg KP, Ancukiewicz M, Bernard GR. 2002. Recovery Rate and Prognosis in Older Persons who Develop Acute Lung Injury and the Acute Respiratory Distress Syndrome. Ann Int Med. 136(1):25-36.

Schoenfeld, DA, Bernard GR. 2002. Statistical Evaluation of Ventilator Free Days as an Efficacy Measure in Clinical Trials of Treatmen for Acute Respiratory Distr. Crit Care Med. 30(8):1772-1777.

Ware, LB, Eisner MD, Thompson BT, Parsons PE, Matthay MA, ARDSNet NIHNHLBI/. 2002. Von Willebrand Factor (VWF), a biochemical marker of endothelial injury, predicts outcome in ALI/ARDS and is not modulated by a . ATS 2002. Abstract

2001

Brower, RG, Ware LB, Berthiaume Y, Matthay MA. 2001. Treatment of ARDS. Chest. 120(4):1347-1367.

Betesky, RA, Schoenfeld DA. 2001. Nonparametric estimation in a cure model with random cure times. Biometrics. 2001(57):1.

Eisner, MD, Hayden D, Thompson BT, Matthay MA. 2001. Airway pressure and the risk of early barotrauma in ALI/ARDS. ATS. Abstract

Rubenfeld, GD, Cooper C, Carter G, Thompson BT, Hudson LD. 2001. Barriers to providing lung protective ventilation to patients with acute lung injury. ATS. Abstract

Suchyta, M, Orme JF, Morris AH. 2001. The changing face of organ failure in ARDS. ATS.

Thompson, DA, Hayden D, Ringwood NJ, Schoenfeld DA, Brower RG. 2001. Clinical outcomes of acute lung injury (ALI) patients with AIDS vs. ALI patients with other comorbid conditions. ATS. Abstract

Girod, A, Gottlieb JE, Yannarell L, Park PK. 2001. Critical care nursing perceptions of pulmonary artery catheter competency and clinical relevance: do nurses know what they know? ATS. Abstract

Lee, CM, Neff MJ, Steinberg KP, Raniery, Slutsky AS, Hudson LD. 2001. Effects of low tidal volume ventilation on intrinsic PEEP in patients with acute lung injury. ATS. Abstract

Brower, RG, Clemmer T, Lanken PN, MacIntyre NR, Matthay MA, Morris AH, Schoenfeld DA, Thompson BT. 2001. Effects of recruitment maneuvers (RMs) in acute lung injury (ALI) patients ventilated with lower tidal volumes and higher positi. ATS. Abstract

Goss, CH, Rubenfeld GD, Brower RG, Hudson LD. 2001. Incidence of acute lung injury and acute respiratory distress syndrome (ALI/ARDS) in the United States. ATS. Abstract

Eisner, MD, Thompson BT, Hudson LD, Luce JM, Hayden D, Schoenfeld DA, Matthay MA, ARDSNet NIHNHLBI/. 2001. Efficacy of Low Tidal Volume Ventilation in Patients with Different Clinical Risk Factors for Acute Lung Injury and the Acute Respiratory Distress Syndrome. Am J Resp Crit Care Med. 164:231-236.

Kallet, RH, Alonso JA, Martin L, Eisner MD, Luce JM, ARDSNet NIHNHLBI/. 2001. Characteristics of acute lung injury patients exhibiting respiratory distress or dyssynchrony during low tidal volume ventilatio. Respir Care. Abstract

Thompson, BT, Hayden D, Matthay MA, Brower RG, Parsons PE. 2001. Clinicians' Approaches to Mechanical Ventilation in Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS). Chest. 120:1622-1627.

Kallet, RH, Corral W, Hayden D, Silverman HJ, Luce JM, ARDSNet NIHNHLBI/. 2001. Does high level minute ventilation VE Demand limit implementation of the acute respiratory distress syndrom (ARDS) network low V. Respir Care. Abstract

Kallet, RH, Corral W, Silverman HJ, Luce JM. 2001. Implementation of a Low Tidal Volume Ventilation Protocol for Patients with Acute Lung Injury or Acute Respiratory Distress Synd. Respir Care. 46(10):1024-1037.

Kallet, RH, Alonso JA, Martin L, Eisner MD, Luce JM, ARDSNet NIHNHLBI/. 2001. Incidence of respiratory distress or patients ventilator dyssynchrony during low tidal volume ventilation in patients with acute. Respir Care. Abstract

Brower, RG. 2001. New ARDS Network Guidelines: Which of your patients will benefit? (Letter) J Crit Illness. 16(6):277.

Morris, AH. 2001. Rational Use of Computerized Protocols in the ICU. Crit Care. 5:249-254.

Kallet, RH, Eisner MD, Luce JM, ARDSNet NIHNHLBI/. 2001. Sedation and neuromuscular blocking agent requirements during initiation of low tidal volume ventilation in patients with acute . Respir Care. Abstract

Silverman, HJ, Hull SC, Sugarman J. 2001. Variability Among Institutional Review Boards' Decisions Within the Context of a Multicenter Trial. Crit Care Med. 29:235-241.

Brower, RG. 2001. Ventilation in acute lung injury and ARDS 6 ml.kg: end of story? Minerva Anestesiologica. 67(4):248-251.

2000

Ely, EW, Wheeler AP, Thompson BT, Steinberg KP, Ancukiewicz M, Bernard GR. 2000. Age is an independent predictor of outcomes in ARDS. ATS. Abstract

Suchyta, M, Lawton C, Morris AH. 2000. ARDS mortality in randomized controlled trials using methods is the same in two different hospitals. ATS. Abstract

Suchyta, M, Orme JF, Morris AH. 2000. ARDS patient mortality is lower and depends on P/F. ATS.

Suchyta, M, Morris AH, Thompson BT, ARDSNet NIHNHLBI/. 2000. Attributes and outcomes of randomized versus excluded patients in ALI/ARDS trials. ATS. Abstract

Gottlieb, JE, Park PK, Girod A, Ancukiewicz M, Hayden D, Schoenfeld DA. 2000. Comparison of neuromusclar blocker and sedative use among patients with ARDS treated with lows versus high tidal volume. ATS. Abstract

Schoenfeld, DA, Thompson BT, Wheeler AP, Lanken PN, ARDSNet NIHNHLBI/. 2000. Early changes in IL-6 as a surrogate marker (SM) for survival in patients with acute lung injury (ALI) or ARDS. ATS. Abstract

Morris, AH, ARDSNet NIHNHLBI/. 2000. Evaluating and refining a hemodynamic protocol for use in a multicenter ARDS clinical trial. ATS. Abstract

Lanken, PN, Schoenfeld DA, Thompson BT, ARDSNet NIHNHLBI/. 2000. Evaluation of early changes in PaO2/FiO2 (P/F) or Oxygenation index (01) as surrogate markers for survival in patients with acut. ATS. Abstract

Abraham, E, Bursten S, Schoenfeld DA. 2000. Free fatty acids as predictors of outcome in ARDS. ATS. Abstract

NIH / NHLBI ARDSNet. 2000. Ketoconazole for early treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome. A randomized trial. JAMA. 283:1995-2002.

Abraham, E, ARDSNet NIHNHLBI/. 2000. Lisofylline versus placebo for ALI and ARDS. ATS. Abstract

Eisner, MD, Thompson BT, Hudson LD, Luce JM, Matthay MA, ARDSNet NIHNHLBI/. 2000. Low tidal volume ventilation reduces mortality independent of the clinical risk factor for ALI/ARDS. ATS. Abstract

Wheeler, AP, Wickersham N, Ancukiewicz M, Brower RG, Thompson BT, Bernard GR, ARDSNet NIHNHLBI/. 2000. Low tidal volume ventilation reduces plasma cytokines in human acute lung injury. ATS. Abstract

Morris, AH. 2000. Oscillation and damping in human decision-making systems. ATS. Abstract

Krishman, JA, Hayden D, Schoenfeld DA, Bernard GR, Brower RG, ARDSNet NIHNHLBI/. 2000. Outcome of participants vs eligible non-participants in a clinical trial of critically ill patients. ATS. Abstract

Suchyta, M, Morris AH, ARDSNet NIHNHLBI/. 2000. Outcomes of ALI/ARDS patients randomized vs excluded for >36 duration of ARDS. ATS. Abstract

Klein, D, Morris AH, ARDSNet NIHNHLBI/. 2000. Variations in tidal volume due to predicted body weight equations. Abstract

Ringwood, NJ, Hayden D, Lanken PN, Luce JM, Thompson BT. 2000. Withholding and withdrawing of life sustaining treatment for patients receiving higher or lower tidal volume ventilation in ARDS. ATS. Abstract

Wiedemann, HP, Matthay MA. 2000. Acute Respiratory Distress Syndrome. Clinics in Chest Medicine. 21

Morris, AH. 2000. Developing and Implementing Computerized Protocols for Standardization of Clinical Decisions. Ann Int Med. 132:373-383.

Brower, RG, Fessler HE. 2000. Mechanical ventilation in acute lung injury and acute respiratory distress syndrome. Clinic in Chest Medicine. 21:491-510.

MacIntyre, NR. 2000. Mechanical ventilation strategies for lung protection. Innovations in Mechanical Ventilation, Seminars in Resp and Crit Care Med. 21 (3):215-222.

MacIntyre, NR. 2000. Mechanical ventilation strategies for parenchymal lung injury. Mechanical Ventilation. :330-339.

MacIntyre, NR. 2000. Principles of Mechanical Ventilation. Textbook of Respiratory Medicine. :2471-2485.

ARDSNet, NIHNHLBI/. 2000. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory . New Engl J Med. 342:1301-1308.

Brower, RG, Matthay MA, Wheeler AP. 2000. Ventilation with lower tidal volumes as compared with traditional volumes for acute lung injury (letter). New Engl J Med. 343:813-814.

Knudsen, N, Fulkerson WF. 2000. Ventilator induced lung injury. Mechanical Ventilation. :212-221.

1999

Thompson, BT, ARDSNet NIHNHLBI/. 1999. Results on the Study on mechanical ventilation. Proceedings of the Berlin ARDS Symposium. :65-59.

Thompson, BT, ARDSNet NIHNHLBI/. 1999. Baseline physiologic assessment and outcome in 234 patients with acute lung injury (ALI). ATS. Abstract

Morris, AH, ARDSNet NIHNHLBI/. 1999. Data sampling interval and acuracy of patient exposure in ARDS. ATS. Abstract

Morris, AH, Orme JF, Clemmer T, Grissom CK, Weaver L, Young MP, East T, Uhler J, Funlinson K, ARDSNet NIHNHLBI/. 1999. Hemodynamic computerized protocol development. ATS. Abstract

Parsons, PE, ARDSNet NIHNHLBI/. 1999. The incidence of non-pulmonary organ failure is independent of Pao2/FiO2 ratio. ATS. Abstract

Parsons, PE, ARDSNet NIHNHLBI/. 1999. Low tidal volume ventilation is routinely used in patients with early acute lung injury. ATS. Abstract

Krishman, JA, Thompson DA, Diette G, Brower RG, ARDSNet NIHNHLBI/. 1999. ALI/ARDS survival after hospital discharge sampling interval and accuracy of patient exposure in ARDS. ATS. Abstract

Brower, RG, ARDSNet NIHNHLBI/. 1999. Assessment of protocol conduct in a trial of ventilator management of acute lung injury (ALI) and ARDS. ATS. Abstract

Krishman, JA, Thompson DA, Diette G, Brower RG, ARDSNet NIHNHLBI/. 1999. PaO2/FiO2 predicts mortality in patients with ALI/ARDS sampling interval and accuracy of patient exposure in ARDS. ATS. Abstract

1998

Brower, RG. 1998. Future clinical trials of mechanical ventilation in ARDS and ALI. Acute Lung Injury.

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